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Cefoperazone 1000mg + Sulbactam 500mg Salt Information :
Uses of Cefoperazone 1000mg + Sulbactam 500mg:
Cefoperazone is a third-generation cephalosporin antibiotic. It is used in the treatment of pseudomonas bacterial infections .
Side Effects of Cefoperazone 1000mg + Sulbactam 500mg:
Rash, skin reactions, fever, eosinophilia, urticaria, and pruritus. Haematological - Slight decreases in Hb conc and haematocrit value. GI effects, diarrhoea or loose stools, nausea, and vomiting. Mild, transient elevations of serum SGOT, SGPT, and alkaline phosphatase concentrations. Renal effects - Transient elevations in BUN and serum creatinine concentrations.
Drug Interactions of Cefoperazone 1000mg + Sulbactam 500mg:
With aminoglycosides: Concomitant admin may increase risk of nephrotoxicity. With heparin/warfarin: Concurrent use may cause marked hypoprothrombinemia and/or prolonged bleeding time.
Contraindications of Cefoperazone 1000mg + Sulbactam 500mg:
Hypersensitivity. Known allergy to penicillins.
Mechanism of Action of Cefoperazone 1000mg + Sulbactam 500mg:
Cefoperazone, a bactericidal antibiotic, inhibits bacterial cell wall synthesis of actively dividing cells by binding to one or more penicillin binding proteins (PBPs). Sulbactam is a β-lactamase inhibitor and acts primarily by irreversible inactivation of β-lactamases.
Special Precautions for Cefoperazone 1000mg + Sulbactam 500mg: