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What are the possible side effects of pantoprazole (Protonix)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using pantoprazole and call your doctor at once if you have symptoms of low magnesium such as:

• fast or uneven heart rate
• jerking muscle movements
• feeling jittery
• diarrhea that is watery or bloody
• muscle cramps, muscle weakness or limp feeling
• cough or choking feeling; or
• headache, trouble concentrating, memory problems, weakness, loss of appetite, feeling unsteady, confusion, hallucinations, fainting, seizure, or shallow breathing.

Less serious side effects are more likely to occur, such as:

• weight changes
• nausea, vomiting, mild diarrhea
• gas, stomach pain
• dizziness, drowsiness, tired feeling
• joint pain; or
• sleep problems (insomnia).