|Product Type||Dry Syrup|
|Dosage Form||As Per Doctor Prescription|
|Composition of Product||Cefixime 50mg /5ml|
|Pack Size||30 ml|
|How to Take||With Water|
|Storage||store in a cool place|
Cefixime 50mg/5ml Salt Information :
Uses of Cefixime 50mg/5ml:
Cefixime uses include treatment of soft tissue infection , lower and upper respiratory tract infections and other infections . Cefixime is used alone or in combination with class of anti-biotics for better coverage .
Side Effects of Cefixime 50mg/5ml:
Diarrhoea, nausea, vomiting, abdominal pain; headache, dizziness, thrombocytopenia, eosinophilia. Potentially Fatal: Pseudomembranous colitis.
Drug Interactions of Cefixime 50mg/5ml:
Increased concentrations with probenecid. Potentially Fatal: May increase prothrombin time with anticoagulants.
Contraindications of Cefixime 50mg/5ml:
Hypersensitivity to cephalosporin.
Mechanism of Action of Cefixime 50mg/5ml:
Cefixime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death. Absorption: Only 40-50% is absorbed from the GI tract (oral); rate may be decreased if taken with food. Greater absorption from oral suspension than tablets. Distribution: Bile, urine (high concentrations); crosses the placenta. Protein-binding: 65%. Excretion: 20% of an oral dose excreted via urine unchanged; 60% nonrenal elimination; some is excreted via the faeces from the bile. Substantially removed by dialysis.
Special Precautions for Cefixime 50mg/5ml:
History of allergy to penicillins; pregnancy, lactation; renal failure; GI disease.